Sixty Percent of Adults Can’t Digest Milk


milk Got milk? If you do, take a moment to ponder the true oddness of being able to drink milk after you’re a baby.

No other species but humans can. And most humans can’t either.

The long lists of food allergies some people claim to have can make it seem as if they’re just finicky eaters trying to rationalize likes and dislikes. Not so. Eggs, peanuts, tree nuts, fish, and gluten all can wreak havoc on the immune system of allergic individuals, even causing a deadly reaction called anaphylaxis.

But those allergic reactions are relatively rare, affecting an estimated 4% of adults.

Milk’s different.

First off, most people who have bad reactions to milk aren’t actually allergic to it, in that it’s not their immune system that’s reponding to the milk.

Instead, people who are lactose intolerant can’t digest the main sugar -lactose- found in milk. In normal humans, the enzyme that does so -lactase- stops being produced when the person is between two and five years old. The undigested sugars end up in the colon, where they begin to ferment, producing gas that can cause cramping, bloating, nausea, flatulence and diarrhea.

If you’re American or European it’s hard to realize this, but being able to digest milk as an adult is one weird genetic adaptation.

It’s not normal. Somewhat less than 40% of people in the world retain the ability to digest lactose after childhood. The numbers are often given as close to 0% of Native Americans, 5% of Asians, 25% of African and Caribbean peoples, 50% of Mediterranean peoples and 90% of northern Europeans. Sweden has one of the world’s highest percentages of lactase tolerant people.

Being able to digest milk is so strange that scientists say we shouldn’t really call lactose intolerance a disease, because that presumes it’s abnormal. Instead, they call it lactase persistence, indicating what’s really weird is the ability to continue to drink milk.

There’s been a lot of research over the past decade looking at why humans stay milk drinkers into adulthood.

A long-held theory was that the mutation showed up first in Northern Europe, where people got less vitamin D from the sun and therefore did better if they could also get the crucial hormone (it’s not really a vitamin at all) from milk.

But now a group at University College London has shown that the mutation actually appeared in dairy farmers who lived in a region between the central Balkans and central Europe.

The paper was published this week in PLoS Computational Biology.

The researchers used a computer to model the spread of lactase persistence, dairy farming, other food gathering practices and genes in Europe.

Today, the highest proportion of people with lactase persistence live in Northwest Europe, especially the Netherlands, Ireland and Scandinavia.

{Elizabeth Weise-USA Today San Francisco/Noam Newscenter}